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Almost all the organs of the body contain some fat. A normal liver contains about 5% fat. When the amount of fat (lipids) in the liver exceeds 10%, healthy liver cells are replaced by fat cells. This condition is known as "Fatty Liver," which causes squeezing of the blood, lymph vessels, and bile ducts, and enlarging the liver. Known causes of fatty liver are alcohol consumption, obesity, diabetes, chemicals, drugs, malnutrition, and Vitamin A toxicity (The Merck Manual).

The rest of the liver is made up of cells called hepatocytes. The rupturing of fat hepatocytes can produce inflammation. This leads to the death of liver cells and the formation of fatty cysts and/or scar tissue. The progression goes from: fatty liver, inflammation, and chaos in microcirculation, cell death, scar tissue, and finally to liver failure.

The liver is the main organ responsible for fat metabolism, glycogen storage for energy, and formation of new cells. If the amount of fat exceeds what the body requires, the fat accumulates in the liver. If the amount of carbohydrates exceeds what the body requires, the excess is converted into fat, which then also accumulates in the liver. The prevalence of fatty liver is the result of a diet high in sugar, animal fats, and alcohol, as well as a sedentary life style.

Fatty liver occurs in alcoholics (see ''Alcoholic Liver Disorders") and in non-drinkers. Until recently, it was believed that in non-alcoholics, a fatty liver was a consequence of being overweight or diabetic. However, new scientific studies have identified it as a separate disease with potentially serious consequences. It is now believed that 10-20% of non-drinkers that have a fatty liver will develop cirrhosis.

As the function of the liver is impaired, several conditions can occur:

• Toxic body: due to decreased cleansing and detoxification.

• Diabetes: due to reduced formation and storage of glycogen.

• Gastrointestinal disorders: due to slowed bile formation and secretion.

A person with a fatty liver does not necessarily seem ill. In fact, commonly there are no symptoms. It can be present even when there is no evidence of abnormalities on physical examination. Fat accumulation is a gradual process that occurs over many years. Eventually, the liver becomes enlarged and can cause a vague discomfort in the right upper abdomen. Severe fatty infiltration of the liver can result in symptoms of weakness, anorexia, nausea, and abdominal discomfort.

It is most important to treat the condition before it can progress into a more serious form.




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